Microsoft Defender for Endpoint (MDE) must enable Memory Content Analysis.

Severity	Group ID	Group Title	Version	Rule ID	Date	STIG Version
medium	V-275995	SRG-APP-000279	MSDE-00-001300	SV-275995r1119725_rule	2025-11-25	1

Description
Malicious code protection mechanisms include, but are not limited to, antivirus and malware detection software. To minimize potential negative impact to the organization that can be caused by malicious code, it is imperative that malicious code is identified and eradicated. This setting automatically investigates memory content of processes. When enabled, memory content can be uploaded to MDE during an Automated investigation.

Description

Malicious code protection mechanisms include, but are not limited to, antivirus and malware detection software. To minimize potential negative impact to the organization that can be caused by malicious code, it is imperative that malicious code is identified and eradicated. This setting automatically investigates memory content of processes. When enabled, memory content can be uploaded to MDE during an Automated investigation.

ℹ️ Check
Access the MDE portal as a user with at least an MDE Administrator or equivalent role: 1. In the navigation pane, select Settings >> Endpoints >> Automation uploads (under Rules). 2. Verify the slide bar for "Memory Content Analysis" is set to "On". If the slide bar for "Memory Content Analysis" is not set to "On", this is a finding.

✔️ Fix
Access the MDE portal as a user with at least an MDE Administrator or equivalent role: 1. In the navigation pane, select Settings >> Endpoints >> Automation uploads (under Rules). 2. Set the slide bar for "Memory Content Analysis" to "On".